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Cidofovir monophosphate – CAS 142276-30-0

Cidofovir monophosphate – CAS 142276-30-0 is synthesized by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

min 95%

Package contents

Cidofovir monophosphate triethylammonium salt

This compound is for research use only. We do not sell to patients.

Amount

1 mg		€ 1500	Stock
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Amount

1 mg

€ 1500

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 142276-30-0

IUPAC name: [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethyl-phosphonooxyphosphinic acid

Other names: CDV monophosphate

Molecular weight: 359.17 g/mol

Molecular formula: C₈H₁₅N₃O₉P₂

InChI: InChI=1S/C8H15N3O9P2/c9-7-1-2-11(8(13)10-7)3-6(4-12)19-5-21(14,15)20-22(16,17)18/h1-2,6,12H,3-5H2,(H,14,15)(H2,9,10,13)(H2,16,17,18)/t6-/m0/s1

Description

Cidofovir monophosphate is an intermediate metabolite of the antiviral drug Cidofovir. It plays a crucial role in the drug’s mechanism of action, although it’s not the final active form.

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Payment

Payment terms 30 days net
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References

Magee, W. C., Hostetler, K. Y., & Evans, D. H. (2005). Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphate. Antimicrobial agents and chemotherapy, 49(8), 3153-3162.
Xiong, X., Smith, J. L., Kim, C., Huang, E. S., & Chen, M. S. (1996). Kinetic analysis of the interaction of cidofovir diphosphate with human cytomegalovirus DNA polymerase. Biochemical pharmacology, 51(11), 1563-1567.
Cundy, K. C. (1999). Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir. Clinical pharmacokinetics, 36(2), 127-143.