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Acyclovir triphosphate – CAS 66341-18-2

Acyclovir triphosphate – CAS 66341-18-2 is synthesized by SigutLabs (Prague, Czech Republic).

Purity (LC-MS)

min 98%

Package contents

Acyclovir triphosphate triethylammonium salt

This compound is for research use only. We do not sell to patients.

Amount

1 mg	€ 450	Stock
5 mg	€ 850	Stock
Do you want custom amount?			Custom amount

Amount

1 mg

€ 450

Stock

5 mg

€ 850

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 66341-18-2

IUPAC name: [2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]ethoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

Other names: AcycloGTP; Acycloguanosine triphosphate; Acyclovir triphosphate;

Molecular weight: 465.14 g/mol

Molecular formula: C₈H₁₄N₅O₁₂P₃

InChI: InChI=1S/C8H14N5O12P3/c9-8-11-6-5(7(14)12-8)10-3-13(6)4-22-1-2-23-27(18,19)25-28(20,21)24-26(15,16)17/h3H,1-2,4H2,(H,18,19)(H,20,21)(H2,15,16,17)(H3,9,11,12,14)

Description

Acyclovir triphosphate is an active antiviral metabolite derived from acyclovir, widely utilized in research focused on antiviral therapeutics. It selectively inhibits viral DNA polymerase, effectively disrupting viral DNA replication. Commonly employed in studies targeting herpes simplex viruses (HSV), varicella-zoster virus (VZV), and related viral pathogens, this compound is particularly valuable for biochemical assays, enzyme kinetics studies, and antiviral drug development.

At SigutLabs, we provide high-quality acyclovir triphosphate suitable for pharmaceutical research and advanced biological applications. Our product ensures consistent purity, stability, and reproducibility, enabling accurate and reliable experimental outcomes.

Chemicals are distributed worldwide

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Shipping through DHL in 48 hours
Sensitive compounds are shipped on dry ice
All compounds are safely and rigorously packed

Payment

Payment terms 30 days net
We are sending the invoice the same day as the shipment
We are able to modify the invoice for the academic institution, so the order can be paid from grants

References

Furman, P. A., St Clair, M. H., & Spector, T. (1984). Acyclovir triphosphate is a suicide inactivator of the herpes simplex virus DNA polymerase. Journal of Biological Chemistry, 259(15), 9575-9579.
Elion, G. B. (1982). Mechanism of action and selectivity of acyclovir. The American journal of medicine, 73(1), 7-13.
Wei, Y. P., Yao, L. Y., Wu, Y. Y., Liu, X., Peng, L. H., Tian, Y. L., … & He, Q. G. (2021). Critical review of synthesis, toxicology and detection of acyclovir. Molecules, 26(21), 6566.