Acyclovir diphosphate – CAS 66341-17-1

Acyclovir diphosphate – CAS 66341-17-1 is synthesized by SigutLabs (Prague, Czech Republic). 

Purity (LC-MS)

min 98%

Package contents

Acyclovir diphosphate triethylammonium salt

This compound is for research use only. We do not sell to patients.

Amount
1 mg
€ 600

Stock

5 mg
€ 1350

Stock

Do you want custom amount?
Custom amount
Amount
1 mg
€ 600

Stock

5 mg
€ 1350

Stock

Do you want custom amount?
Custom amount

Characterisation

CAS: 66341-17-1
IUPAC name: 2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]ethyl phosphono hydrogen phosphate
Other names: Acyclovir Diphosphate; ACV-DP
Molecular weight: 385.16 g/mol
Molecular formula: C8H13N5O9P2
InChI: InChI=1S/C8H13N5O9P2/c9-8-11-6-5(7(14)12-8)10-3-13(6)4-20-1-2-21-24(18,19)22-23(15,16)17/h3H,1-2,4H2,(H,18,19)(H2,15,16,17)(H3,9,11,12,14)

Description

Acyclovir diphosphate is an active antiviral metabolite derived from acyclovir, widely utilized in research focused on antiviral therapeutics. It selectively inhibits viral DNA polymerase, effectively disrupting viral DNA replication. Commonly employed in studies targeting herpes simplex viruses (HSV), varicella-zoster virus (VZV), and related viral pathogens, this compound is particularly valuable for biochemical assays, enzyme kinetics studies, and antiviral drug development.

At SigutLabs, we provide high-quality acyclovir diphosphate suitable for pharmaceutical research and advanced biological applications. Our product ensures consistent purity, stability, and reproducibility, enabling accurate and reliable experimental outcomes.

 

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Payment

  • Payment terms 30 days net
  • We are sending the invoice the same day as the shipment
  • We are able to modify the invoice for the academic institution, so the order can be paid from grants

References

  • Furman, P. A., St Clair, M. H., & Spector, T. (1984). Acyclovir triphosphate is a suicide inactivator of the herpes simplex virus DNA polymerase. Journal of Biological Chemistry259(15), 9575-9579.
  • Elion, G. B. (1982). Mechanism of action and selectivity of acyclovir. The American journal of medicine73(1), 7-13.
  • Wei, Y. P., Yao, L. Y., Wu, Y. Y., Liu, X., Peng, L. H., Tian, Y. L., … & He, Q. G. (2021). Critical review of synthesis, toxicology and detection of acyclovir. Molecules26(21), 6566.
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