Webinar, April 22: ADC Performance by Design – From Linker Chemistry to Bioanalytical Insight
SigutLabs, in collaboration with Conscio Group, invites professionals in the biopharmaceutical sector to a focused technical webinar on the drivers of Antibody-Drug Conjugate (ADC) performance.
The session features Alessandro Panattoni, Head of Chemistry at SigutLabs, who will examine the critical role of organic chemistry in optimizing ADC stability and addressing linker-payload incompatibility.

Event Details
Topic: ADC Performance by Design: From Linker Chemistry to DAR and Bioanalytical Insight
Date: Wednesday, April 22, 2:00 PM CET
Registration: Register via Microsoft Teams
Cost: Complimentary
In this session, Alessandro Panattoni will provide practical insights into:
Linker Design: Its influence on key ADC properties, including stability, hydrophilicity, and aggregation behavior.
Conjugation Strategy: How chemistry dictates DAR (Drug-to-Antibody Ratio) control and overall conjugate performance.
Case Study: Practical methods to overcome linker-payload incompatibility through advanced synthetic routes.
Program Overview
The webinar will be hosted by Jiří Raška (CCO, Conscio Group), providing market insights, followed by technical presentations from:
Alessandro Panattoni (SigutLabs): The Organic Chemist’s Role in Enhancing ADC Performance.
Milan Maděra (Conscio Group): Integrated Analytical and Bioanalytical Strategies for Next-Generation Biotherapeutics.
The session will conclude with a live Q&A, offering attendees the opportunity to discuss specific challenges in ADC development.
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