Sigut

Webinar, April 22: ADC Performance by Design – From Linker Chemistry to Bioanalytical Insight

March 20, 2026

SigutLabs, in collaboration with Conscio Group, invites professionals in the biopharmaceutical sector to a focused technical webinar on the drivers of Antibody-Drug Conjugate (ADC) performance.

The session features Alessandro Panattoni, Head of Chemistry at SigutLabs, who will examine the critical role of organic chemistry in optimizing ADC stability and addressing linker-payload incompatibility.

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Event Details

  • Topic: ADC Performance by Design: From Linker Chemistry to DAR and Bioanalytical Insight

  • Date: Wednesday, April 22, 2:00 PM CET

  • Registration: Register via Microsoft Teams

  • Cost: Complimentary


In this session, Alessandro Panattoni will provide practical insights into:

  • Linker Design: Its influence on key ADC properties, including stability, hydrophilicity, and aggregation behavior.

  • Conjugation Strategy: How chemistry dictates DAR (Drug-to-Antibody Ratio) control and overall conjugate performance.

  • Case Study: Practical methods to overcome linker-payload incompatibility through advanced synthetic routes.

Program Overview

The webinar will be hosted by Jiří Raška (CCO, Conscio Group), providing market insights, followed by technical presentations from:

  • Alessandro Panattoni (SigutLabs): The Organic Chemist’s Role in Enhancing ADC Performance.

  • Milan Maděra (Conscio Group): Integrated Analytical and Bioanalytical Strategies for Next-Generation Biotherapeutics.

The session will conclude with a live Q&A, offering attendees the opportunity to discuss specific challenges in ADC development.

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