Chemical consulting

De-risk your decisions with lab-backed chemical consulting services

Sigut
Thumbnail image Chemical consulting

Turn complex chemistry into clear next steps

For R&D-intensive manufacturers and process plants seeking scalable routes and de-risked choices, our chemical consulting services deliver decision-ready clarity. As your chemistry consulting group, we run focused literature/database reviews, lay out options and trade-offs, and give you a clear go/no-go with next steps.

Unlike many chemical consulting companies, we pair chemistry advisory with an in-house lab. Our laboratory consulting services hand off to contract research, custom synthesis, or scale-up, so plans are testable without losing context. Over 12+ years, this approach has guided 100+ projects worldwide.

Where relevant, we support small-molecule drug discovery and drug development consulting, from drug design in medicinal chemistry to preclinical drug development.

Thumbnail image Chemical consulting

Partner with us to save

Time
on internal scoping and alignment
Decision risk
on guesswork and blind spots
Expertise & tools
on niche hires and premium software
consulting image

Chemistry consulting scenarios
we support most often

mask molecul
molecul blue
Patent and database review to validate licensed chemical process data
Bringing a new chemistry-based product to market under a purchased licence?
View more
mask molecul
molecul blue
Independent chemistry review for process improvement and innovation
Running a chemical production, but under pressure to improve?
View more
mask molecul
molecul blue
Chemistry feasibility and decision support for biotech startups and spin-offs
Leading a biotech startup or university spin-off, but lacking in-house chemistry?
View more
mask molecul
molecul blue
On-demand chemistry troubleshooting for stalled R&D and production
Stuck with a chemistry problem you cannot resolve in-house?
View more
mask molecul
molecul blue
Chemical sourcing and supplier verification for hard-to-source chemicals
Need a specific chemical but cannot source it?
View more
Contact
Get in touch photo
Do you want to solve your chemistry project?
Get in touch
Contact
Get in touch photo
Do you want to solve your chemistry project?
Get in touch
expertise image

We also bring chemical
expertise to areas like

mask molecul
molecul blue
De-risking chemistry due diligence for investors and venture funds
mask molecul
molecul blue
Optimal synthetic route assessment and scouting to unlock scale-up
mask molecul
molecul blue
Lab-to-pilot tech transfer troubleshooting to avoid failed runs
mask molecul
molecul blue
Chemical production review to reduce cost and improve process economy
mask molecul
molecul blue
Independent chemistry second opinion to sharpen R&D strategy
mask molecul
molecul blue
Chemistry consulting for small-molecule drug discovery and development
mask molecul
molecul blue
Problem framing and solution scouting for non-obvious chemistry challenges

Bring in top chemists without hiring

Our customers include
Start-Ups
We assist small start-ups in exploring their novel ideas, e.g., in order to obtain preliminary data for investors.
Spin-offs
We provide laboratory services to spin-offs lacking their own facilities dedicated to complex organic synthesis.
Universities
We offer budget-friendly research for universities to build on and provide unique substances that are not commercially available.
Pharma
We assist large pharmaceutical companies with synthesis so that they can focus on more difficult aspects of drug development.
Biotech
We have years of experience in organic, bioorganic, and medicinal chemistry, taking your projects to the next level.
Medical
We specialize in antiviral nucleosides and nucleotides, but we are always interested in novel and challenging syntheses.

If you haven´t found your area listed above, feel free to contact us and we will let you know how we can help. We are ready to rise to any challenge.

icon molekula
“Sigut Labs' ability to rapidly adapt and optimize the synthesis process was impressive. They efficiently scaled up production and delivered gram quantities within weeks. I am convinced that making pro-N6pA commercially available through Sigut Labs will significantly benefit the scientific community by simplifying access to this vital research tool.”
Dr. Pavel Kielkowski /Kielkowski Research Group/
“Our molecule is now in the preclinical phase thanks to scale up done by the SigutLabs team.”
Dr. Jiří Janata /Institute of Microbiology of the Czech Academy of Sciences/
“SigutLabs supported our research by providing custom-synthesized ddhC-derived nucleotide analogues, which were essential for our Viperin-related studies and for generating preliminary data supporting future grant applications. We greatly valued their scientific expertise, particularly their guidance in selecting the most appropriate molecular formats, as well as the speed, quality, and reliability of their custom synthesis services. All compounds were delivered promptly, at excellent purity, and were immediately suitable for use in our experimental assays.”
Assistant senior lecturer Soham Gupta /Karolinska Institutet Sweden/
“We were really surprised that such a small company was able to develop an innovative technology that enabled the purification of large quantities of our crude product. Moreover, in such a short time. Job well done!”
Ralphy Cooper /Independent Consultant/
“The compounds we received are of high quality. The accompanying information is helpful for us in designing our experiments.”
Professor Anthony Leung /Johns Hopkins University/
“Collaborating with SigutLabs on our CDK and GSK inhibitor research was a game-changer. Their expertise proved very useful in transforming our initial research concepts into a robust scientific program.”
Assoc. Professor Milan Jakubek /First Faculty of Medicine, Charles University/

How we work

Take a sneak peek into our processes
1. INQUIRY
When contacted, we typically respond within 24 hours, providing as much information as possible straight away.
2. NDA
Ensuring the confidentiality of your data is our top priority from the very first moment. Typically, we sign a non-disclosure agreement before the first client meeting where relevant.
3. KICK-OFF
After the client accepts our offer, we're prepared to assist in scaling up your process or synthesizing your desired products on a large scale. We provide custom quantities ranging from 1 mg to 10 kg of the final product. We aim to identify efficient pathways that reduce reaction steps and purifications, ultimately saving time and costs.
4. PROCEDURE
We employ state-of-the-art automated flash chromatography systems by ECOM, using columns from 4 g to 5 kg of silica or C18 for purifying complex reaction mixtures up to 200 g. For intermediate purifications, smaller silica columns or preparative TLCs are used, while traditional techniques like crystallization, distillation, or precipitation are applied in some scale-up syntheses.
5. SHIPPING
If necessary, final products are lyophilized before shipment. To assure optimal shipment conditions for unstable chemicals, we also ship on dry ice to most destinations globally via DHL. Delivery timelines are typically within 24 hours in Europe and 48 hours elsewhere in the world.

What questions
clients often ask

We typically reply within 24–48 hours to confirm the basics and understand your needs. After that, we’ll share a realistic start date based on the scope and any upfront research. In many cases, we can start almost immediately, while formalities (NDA, contract) may take longer than the technical kickoff.

Confidentiality is a priority from the very beginning. If your project is sensitive, we can sign an NDA before the first call. We keep communication and documentation strictly on a need-to-know basis and never share client information or project details externally.

Most consulting is done online, and that is often the most efficient format. If an in-person meeting is useful, we can travel, ideally within Europe, on a case-by-case basis. We focus on chemistry-driven consulting, not on-site equipment inspections.

An initial call to understand your needs and define the scope is usually free of charge. In some cases, we can also do a small, time-limited upfront check (e.g., a quick database scan) to assess feasibility. Any deeper work is always agreed in advance.

We usually price per project, based on a clearly defined scope and deliverables. For example, a literature and patent review can be scoped as a 3-day effort with a fixed price. This approach keeps budgeting predictable and aligns expectations on both sides.

Typically, no. Consulting is scoped and paid as a professional service with defined deliverables. For selected projects, we can discuss a hybrid model (fixed fee plus a success component), depending on the engagement.

We have completed multiple consulting projects, including technical due diligence (e.g., validating data from a purchased license before investment decisions). Due to confidentiality, we usually can’t share detailed examples, but we can discuss relevant experience at a high level and provide testimonials where possible.

Your project is handled by a team of PhD chemists with international experience across multiple areas of chemistry. We assign team members based on the specific nature of the task, so you get the right expertise for your topic. You’ll know who is involved and who your main point of contact is.

Deliverables depend on the project, but you will typically receive a digital written report and an online call to review findings and recommendations. A literature and patent review may include key sources, synthesis insights, and proposed validation experiments. If needed, we can also arrange physical delivery.
Contact
Kryštof

Get in touch

Krystof Sigut, CEO and Founder

Our services

What we excel in so you don’t have to

Thumbnail image Custom synthesis

Custom synthesis

Providing for a custom synthesis of previously reported molecules using described synthetic procedures.

View more
Thumbnail image Contract research

Contract research

Developing novel synthetic routes to provide undescribed compounds in organic, bioorganic, and medicinal chemistry.

View more
Thumbnail image Scale-Up

Scale-Up

Helping you go from lab scales to an industrial scale by applying our cutting-edge instrumentation.

View more
Thumbnail image ADC linkers

ADC linkers

Power your antibody drug conjugates with bespoke linker chemistry

View more

Partners & distributors

logo partner
logo partner
logo partner
logo partner
logo partner
logo partner
logo partner
logo partner
logo partner
logo partner
logo partner
logo partner