Custom synthesis

Gain exclusive access to tailor-made compounds with custom synthesis

Sigut
Thumbnail image Custom synthesis

Beat the obstacle of commercial unavailability

Our top-tier experts provide for custom synthesis of previously reported molecules and well-known compounds using described synthetic procedures. They help you outsmart the challenges of lengthy in-house synthesis of desired products without worrying about purity, deadlines, or regulatory compliance. 

Whether a small startup company or a pharmaceutical giant, we are ready to handle your synthesis challenges by using our state-of-the-art laboratory equipment, analytical instrumentation, and a seasoned team of Ph.D. chemists.

You can rest assured with our accurate price calculations and lead time estimates which are based on detailed preparation work and feasibility studies. When needed, we are also ready to handle large-scale custom synthesis projects.

Thumbnail image Custom synthesis

Partner with us to save

Money
on running your in-house laboratory
Time and effort
on lengthy internal synthesis processes
Staff and capacities
for your core business activities
icon molekula

Unlock your potential
with our chemical expertise

We are seasoned in
icon molekula
Linker-payloads for ADCs
icon molekula
Nucleoside/nucleotide chemistry
icon molekula
Antiviral and antibiotic compounds
icon molekula
Fluorescent labels
icon molekula
Advanced intermediates
icon molekula
Peptide chemistry
icon molekula
Click-chemistry
icon molekula
Organometallic chemistry
icon molekula
Heterocyclic chemistry
icon molekula
Supramolecular chemistry

Thanks to our extensive medicinal and organic chemistry understanding, we also often come up with novel synthetic pathways that are easier to use and shorter. We are also experts in developing novel synthetic routes within contract research and in helping clients scale up their concepts from milligrams to the industrial scale.

If you don’t see your area listed above, feel free to contact us, and we will let you know how we can help. We are ready to rise to any challenge.

Streamline your synthesis projects

Our customers include
Start-ups
We assist small start-ups in exploring their novel ideas, e.g., in order to obtain preliminary data for investors.
Spin-offs
We provide laboratory services to spin-offs lacking their own facilities dedicated to complex organic synthesis.
Universities
We offer budget-friendly research for universities to build on and provide unique substances that are not commercially available.
Pharma
We assist large pharmaceutical companies with synthesis so that they can focus on more difficult aspects of drug development.
Biotech
We have years of experience in organic, bioorganic, and medicinal chemistry, taking your projects to the next level.
Medical
We specialize in antiviral nucleosides and nucleotides, but we are always interested in novel and challenging syntheses.
icon molekula
“Sigut Labs' ability to rapidly adapt and optimize the synthesis process was impressive. They efficiently scaled up production and delivered gram quantities within weeks. I am convinced that making pro-N6pA commercially available through Sigut Labs will significantly benefit the scientific community by simplifying access to this vital research tool.”
Dr. Pavel Kielkowski /Kielkowski Research Group/
“Our molecule is now in the preclinical phase thanks to scale up done by the SigutLabs team.”
Dr. Jiří Janata /Institute of Microbiology of the Czech Academy of Sciences/
“We were really surprised that such a small company was able to develop an innovative technology that enabled the purification of large quantities of our crude product. Moreover, in such a short time. Job well done!”
Ralphy Cooper /Independent Consultant/
“The compounds we received are of high quality. The accompanying information is helpful for us in designing our experiments.”
Professor Anthony Leung /Johns Hopkins University/
“Collaborating with SigutLabs on our CDK and GSK inhibitor research was a game-changer. Their expertise proved very useful in transforming our initial research concepts into a robust scientific program.”
Assoc. Professor Milan Jakubek /First Faculty of Medicine, Charles University/

How we work

Take a sneak peek into our processes
1. INQUIRY
When contacted, we typically respond within 24 hours, providing as much information as possible straight away. To accurately calculate product amounts and estimate lead times, we conduct feasibility studies using reference materials and chemical databases.
2. NDA
Ensuring the confidentiality of your data is our top priority from the very first moment. Typically, we sign a non-disclosure agreement before the first client meeting where relevant.
3. KICK-OFF
Once the client accepts our offer, one of our chemists assumes project management for custom synthesis. If any issue arises, the entire team puts their hands and brains together to find a solution.
4. PROCEDURE
Upon successful synthesis completion, the product undergoes refinement to achieve the necessary purity. We use our in-house LC-MS and NMR for purity analysis. Normally, we furnish clients with LC-MS chromatograms and 1H NMR data. After confirming the structure and purity through analysis, the final product is shipped in custom quantities ranging from 1 mg to 100 g.
5. SHIPPING
If necessary, final products are lyophilized before shipment. To assure optimal shipment conditions for unstable chemicals, we also ship on dry ice to most destinations globally via DHL. Delivery timelines are typically within 24 hours in Europe and 48 hours elsewhere in the world.

What questions
clients often ask

Yes, you can pay by card or bank transfer. New customers are asked for advance payment. We send invoices on the same day as the shipment. We also offer invoice modifications for academic institutions, facilitating payment through grants.

If you can’t find the information you need on a product sheet, feel free to reach out to us at lab@sigutlabs.com. We’ll strive to reply to you as soon as possible.

Each package is meticulously packed. For temperature-sensitive compounds, we ensure shipping on dry ice. We rely on DHL service for worldwide shipments. Typically, packages arrive within 24 hours in the EU and within 48-72 hours elsewhere (subject to customs delays) and we provide a tracking number for every package.

Yes, our products are exclusively for research and development purposes. They cannot be used or sold for treating patients, animals, etc.

Rest assured, the confidentiality of your data is our utmost priority right from the start. Typically, we sign a non-disclosure agreement before our initial meeting with a client.

If you need to make a purchase for a university and are required to get an official quote before placing the order, please contact us at lab@sigutlabs.com. We will send you an official quote within 24 hours.
Contact
Kryštof

Get in touch

Krystof Sigut, CEO and Founder

Our services

What we excel in so you don’t have to

View more
Thumbnail image Contract research

Contract research

Developing novel synthetic routes to provide undescribed compounds in organic, bioorganic, and medicinal chemistry.

Thumbnail image Scale-Up

Scale-Up

Helping you go from lab scales to an industrial scale by applying our cutting-edge instrumentation.

Partners & distributors

logo partner
logo partner
logo partner
logo partner
logo partner
logo partner
logo partner
logo partner
logo partner
logo partner
logo partner
logo partner