Troxacitabine – CAS 145918-75-8
Troxacitabine – CAS 145918-75-8 is synthesised by Sigut Labs (Prague, Czech Republic).
Purity (LC-MS)
97%+
Package contents
Troxacitabine
This compound is for research use only. We do not sell to patients.
Amount
| 100 mg | € 2500 | Stock | ||
| Do you want custom amount? | Custom amount | |||
Amount
100 mg
€ 2500
Stock
Do you want custom amount?
Custom amount
Characterisation
CAS: 145918-75-8
IUPAC name: 4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one
Other names: Troxatyl; Bch-4556; (-)-ODDC
Molecular weight: 213.19 g/mol
Molecular formula: C8H11N3O4
InChI: InChI=1S/C8H11N3O4/c9-5-1-2-11(8(13)10-5)6-4-14-7(3-12)15-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m0/s1
Description
Troxacitabine is being studied in patients with refractory lymphoproliferative diseases.
Chemicals are distributed worldwide
Buy Troxacitabine now, and get your order in 48 hours
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Payment
- Payment terms 30 days net
- We are sending the invoice the same day as the shipment
- We are able to modify the invoice for the academic institution, so the order can be paid from grants
References
- Gourdeau, H., Clarke, M. L., Ouellet, F., Mowles, D., Selner, M., Richard, A., … & Cass, C. E. (2001). Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines. Cancer research, 61(19), 7217-7224.
- Sabini, E., Hazra, S., Konrad, M., Burley, S. K., & Lavie, A. (2007). Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase. Nucleic acids research, 35(1), 186-192.
- Bouffard, D. Y., Jolivet, J., Leblond, L., Hamelin, B., Ouellet, F., Barbeau, S., … & Gourdeau, H. (2003). Complementary antineoplastic activity of the cytosine nucleoside analogues troxacitabine (Troxatyl) and cytarabine in human leukemia cells. Cancer chemotherapy and pharmacology, 52, 497-506.
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