PSI 7411– CAS 1015073-43-4
PSI 7411 – CAS 1015073-43-4 is synthesized by Sigut Labs (Prague, Czech Republic).
Purity (LC-MS)
98%+
Package contents
PSI 7411 triethylammonium salt
This compound is for research use only. We do not sell to patients.
Amount
1 mg | € 1000 | Stock | ||
5 mg | € 2500 | Stock | ||
Do you want custom amount? | Custom amount |
Amount
1 mg
€ 1000
Stock
5 mg
€ 2500
Stock
Do you want custom amount?
Custom amount
Characterisation
CAS: 1015073-43-4
IUPAC name: [(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methyl dihydrogen phosphate
Other names: psi-7411, Sofosbuvir monophosphate, Sofosbuvir-MP, GS-606965
Molecular weight: 340.20 g/mol
Molecular formula: C10H14FN2O8P
InChI: InChI=1S/C10H14FN2O8P/c1-10(11)7(15)5(4-20-22(17,18)19)21-8(10)13-3-2-6(14)12-9(13)16/h2-3,5,7-8,15H,4H2,1H3,(H,12,14,16)(H2,17,18,19)/t5-,7-,8-,10-/m1/s1
Description
PSI 7411 is the a metabolite of Sofosbuvir (PSI-7977). Sofosbuvir (PSI-7977) is a selective and highly active nucleotide analogue inhibitor of HCV.
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Payment
- Payment terms 30 days net
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References
- Lam, A. M., Murakami, E., Espiritu, C., Steuer, H. M. M., Niu, C., Keilman, M., … & Furman, P. A. (2010). PSI-7851, a pronucleotide of β-D-2′-deoxy-2′-fluoro-2′-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication. Antimicrobial agents and chemotherapy, 54(8), 3187-3196.
- Murakami, E., Tolstykh, T., Bao, H., Niu, C., Steuer, H. M. M., Bao, D., … & Furman, P. A. (2010). Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977. Journal of biological chemistry, 285(45), 34337-34347.
- Lam, A. M., Espiritu, C., Bansal, S., Micolochick Steuer, H. M., Niu, C., Zennou, V., … & Furman, P. A. (2012). Genotype and subtype profiling of PSI-7977 as a nucleotide inhibitor of hepatitis C virus. Antimicrobial agents and chemotherapy, 56(6), 3359-3368.
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