PSI 7410 – CAS 1015073-44-5

PSI 7410 – CAS 1015073-44-5 is synthesized by Sigut Labs (Prague, Czech Republic). 

Purity (LC-MS)

98%+

Package contents

PSI 7410 triethylammonium salt

This compound is for research use only. We do not sell to patients.

Amount
1 mg
€ 1200

Stock

5 mg
€ 2700

Stock

Do you want custom amount?
Custom amount
Amount
1 mg
€ 1200

Stock

5 mg
€ 2700

Stock

Do you want custom amount?
Custom amount

Characterisation

CAS: 1015073-44-5
IUPAC name: [(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methyl trihydrogen diphosphate
Other names: psi-7410, Sofosbuvir diphosphate, Sofosbuvir-DP
Molecular weight: 420.18 g/mol
Molecular formula: C10H15FN2O11P2
InChI: InChI=1S/C10H15FN2O11P2/c1-10(11)7(15)5(4-22-26(20,21)24-25(17,18)19)23-8(10)13-3-2-6(14)12-9(13)16/h2-3,5,7-8,15H,4H2,1H3,(H,20,21)(H,12,14,16)(H2,17,18,19)/t5-,7-,8-,10-/m1/s1

Description

PSI 7410 is the ametabolite of Sofosbuvir (PSI-7977). Sofosbuvir (PSI-7977) is a selective and highly active nucleotide analogue inhibitor of HCV.

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Payment

  • Payment terms 30 days net
  • We are sending the invoice the same day as the shipment
  • We are able to modify the invoice for the academic institution, so the order can be paid from grants

References

  • Lam, A. M., Murakami, E., Espiritu, C., Steuer, H. M. M., Niu, C., Keilman, M., … & Furman, P. A. (2010). PSI-7851, a pronucleotide of β-D-2′-deoxy-2′-fluoro-2′-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication. Antimicrobial agents and chemotherapy54(8), 3187-3196.
  • Murakami, E., Tolstykh, T., Bao, H., Niu, C., Steuer, H. M. M., Bao, D., … & Furman, P. A. (2010). Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977. Journal of biological chemistry285(45), 34337-34347.
  • Lam, A. M., Espiritu, C., Bansal, S., Micolochick Steuer, H. M., Niu, C., Zennou, V., … & Furman, P. A. (2012). Genotype and subtype profiling of PSI-7977 as a nucleotide inhibitor of hepatitis C virus. Antimicrobial agents and chemotherapy56(6), 3359-3368.
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