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Mizoribine – CAS 50924-49-7

Mizoribine – CAS 50924-49-7 is synthesised by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

95%+

Package contents

Mizoribine

This compound is for research use only. We do not sell to patients.

Amount

100 mg		€ 300	Stock
Do you want custom amount?				Custom amount

Amount

100 mg

€ 300

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 50924-49-7

IUPAC name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxyimidazole-4-carboxamide

Other names: bredinin; MZB

Molecular weight: 259.22 g/mol

Molecular formula: C₉H₁₃N₃O₆

InChI: InChI=1S/C9H13N3O6/c10-7(16)4-8(17)12(2-11-4)9-6(15)5(14)3(1-13)18-9/h2-3,5-6,9,13-15,17H,1H2,(H2,10,16)/t3-,5-,6-,9-/m1/s1

Description

Mizoribine (brand name Bredinin) is used as an immunosuppressive drug. Mizoribine (MZB) is an imidazole nucleoside that has been used in renal transplantation, and in steroid-resistant nephrotic syndrome, IgA nephropathy, lupus, as well as for adults with rheumatoid arthritis, lupus nephritis and other rheumatic diseases

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Payment

Payment terms 30 days net
We are sending the invoice the same day as the shipment
We are able to modify the invoice for the academic institution, so the order can be paid from grants

References

Yokota, S. (2002). Mizoribine: mode of action and effects in clinical use. Pediatrics international, 44(2), 196-198.
Turka, L. A., Dayton, J., Sinclair, G., Thompson, C. B., & Mitchell, B. S. (1991). Guanine ribonucleotide depletion inhibits T cell activation. Mechanism of action of the immunosuppressive drug mizoribine. The Journal of clinical investigation, 87(3), 940-948.