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1-(tert-butyl)-3-cyclobutyl-5-phenyl-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one – CAS 820233-52-1

1-(tert-butyl)-3-cyclobutyl-5-phenyl-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one – CAS 820233-52-1 is synthesised by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

95%+

Package contents

1-(tert-butyl)-3-cyclobutyl-5-phenyl-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one

This compound is for research use only. We do not sell to patients.

Amount

10 mg	€ 800	Stock
50 mg	€ 2000	Stock
Do you want custom amount?			Custom amount

Amount

10 mg

€ 800

Stock

50 mg

€ 2000

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 820233-52-1

IUPAC name: 1-(tert-butyl)-3-cyclobutyl-5-phenyl-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one

Other names:

Molecular weight: 321.42 g/mol

Molecular formula: C₂₀H₂₃N₃O

InChI: InChI=1S/C20H23N3O/c1-20(2,3)23-18-16(17(22-23)14-10-7-11-14)12-15(19(24)21-18)13-8-5-4-6-9-13/h4-6,8-9,12,14H,7,10-11H2,1-3H3,(H,21,24)

Description

1-(tert-butyl)-3-cyclobutyl-5-phenyl-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one is a unique building block. Related compounds were studied for their properties to inhibit cyclin-dependent kinases (CDK) and glycogen synthase kinase 3 (GSK-3).

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Payment

Payment terms 30 days net
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References

Vidula, N., & Rugo, H. S. (2016). Cyclin-dependent kinase 4/6 inhibitors for the treatment of breast cancer: a review of preclinical and clinical data. Clinical breast cancer, 16(1), 8-17.
Wager, T., T. Pyrazolo`3,4-bipiridin-6-ones as GSK-3 inhibitors. 2005, patent number WO2005000303.