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N4-Hydroxycytidine – CAS 3258-02-4

N⁴-Hydroxycytidine – CAS 3258-02-4 is synthesised by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

97%+

Package contents

N⁴-Hydroxycytidine

This compound is for research use only. We do not sell to patients.

Amount

1 g	€ 850	Stock
100 mg	€ 250	Stock
Do you want custom amount?			Custom amount

Amount

1 g

€ 850

Stock

100 mg

€ 250

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 3258-02-4

IUPAC name: 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-(hydroxyamino)pyrimidin-2(1H)-one

Other names: EIDD-1931, NHC, β-D-N4-hydroxycytidine

Molecular weight: 259.22 g/mol

Molecular formula: C₉H₁₃N₃O₆

InChI: InChI=1S/C9H13N3O6/c13-3-4-6(14)7(15)8(18-4)12-2-1-5(11-17)10-9(12)16/h1-2,4,6-8,13-15,17H,3H2,(H,10,11,16)/t4-,6-,7-,8-/m1/s1

Description

EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV). Molnupiravir is a prodrug of this nucleoside.

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Payment

Payment terms 30 days net
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References

Barnard, D. L., Hubbard, V. D., Burton, J., Smee, D. F., Morrey, J. D., Otto, M. J., & Sidwell, R. W. (2004). Inhibition of severe acute respiratory syndrome-associated coronavirus (SARSCoV) by calpain inhibitors and β-D-N4-hydroxycytidine. Antiviral Chemistry and Chemotherapy, 15(1), 15-22.
Janion, C., & Glickman, B. W. (1980). N4-hydroxycytidine: a mutagen specific for AT to GC transitions. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 72(1), 43-47.