Entecavir – CAS 142217-69-4
Entecavir – CAS 142217-69-4 is synthesized by Sigut Labs (Prague, Czech Republic).
Purity (LC-MS)
min 95%
Package contents
Entecavir
This compound is for research use only. We do not sell to patients.
Amount
50 mg | € 250 | Stock | ||
100 mg | € 400 | Stock | ||
Do you want custom amount? | Custom amount |
Amount
50 mg
€ 250
Stock
100 mg
€ 400
Stock
Do you want custom amount?
Custom amount
Characterisation
CAS: 142217-69-4
IUPAC name: 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one
Other names: Baraclude, BMS 200475
Molecular weight: 277.28 g/mol
Molecular formula: C12H15N5O3
InChI: InChI=1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8-/m0/s1
Description
Entecavir is a potent and selective hepatitis B virus reverse transcriptase inhibitor (EC50 = 3 nM); guanine analog. Inhibits hepatitis B virus replication in HepG2.2.15 cells. Displays selectively over HCMV, HSV-1, VZV, HIV and influenza (EC50 values are 15, 32, 30-60, >10 and >80 μM respectively). Orally bioavailable.
Chemicals are distributed worldwide
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Payment
- Payment terms 30 days net
- We are sending the invoice the same day as the shipment
- We are able to modify the invoice for the academic institution, so the order can be paid from grants
References
- Honkoop, P., & De Man, R. A. (2003). Entecavir: a potent new antiviral drug for hepatitis B. Expert opinion on investigational drugs, 12(4), 683-688.
- Shaw, T., & Locarnini, S. (2004). Entecavir for the treatment of chronic hepatitis B. Expert review of anti-infective therapy, 2(6), 853-871.
- Zoulim, F. (2006). Entecavir: a new treatment option for chronic hepatitis B. Journal of clinical virology, 36(1), 8-12.
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