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Entecavir – CAS 142217-69-4

Entecavir – CAS 142217-69-4 is synthesized by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

min 95%

Package contents

Entecavir

This compound is for research use only. We do not sell to patients.

Amount

50 mg	€ 250	Stock
100 mg	€ 400	Stock
Do you want custom amount?			Custom amount

Amount

50 mg

€ 250

Stock

100 mg

€ 400

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 142217-69-4

IUPAC name: 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one

Other names: Baraclude, BMS 200475

Molecular weight: 277.28 g/mol

Molecular formula: C₁₂H₁₅N₅O₃

InChI: InChI=1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8-/m0/s1

Description

Entecavir is a potent and selective hepatitis B virus reverse transcriptase inhibitor (EC₅₀ = 3 nM); guanine analog. Inhibits hepatitis B virus replication in HepG2.2.15 cells. Displays selectively over HCMV, HSV-1, VZV, HIV and influenza (EC₅₀ values are 15, 32, 30-60, >10 and >80 μM respectively). Orally bioavailable.

Chemicals are distributed worldwide

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Payment

Payment terms 30 days net
We are sending the invoice the same day as the shipment
We are able to modify the invoice for the academic institution, so the order can be paid from grants

References

Honkoop, P., & De Man, R. A. (2003). Entecavir: a potent new antiviral drug for hepatitis B. Expert opinion on investigational drugs, 12(4), 683-688.
Shaw, T., & Locarnini, S. (2004). Entecavir for the treatment of chronic hepatitis B. Expert review of anti-infective therapy, 2(6), 853-871.
Zoulim, F. (2006). Entecavir: a new treatment option for chronic hepatitis B. Journal of clinical virology, 36(1), 8-12.