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Azithromycin – CAS 83905-01-5

Azithromycin – CAS 83905-01-5 is provided by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

98 %

Package contents

Azithromycin hydrate

This compound is for research use only. We do not sell to patients.

Amount

100 mg	€ 100	Stock
1 g	€ 200	Stock
Do you want custom amount?			Custom amount

Amount

100 mg

€ 100

Stock

1 g

€ 200

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 83905-01-5

IUPAC name: (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one

Other names: Azadose; Goxal; Sumamed; Ultreon; CP 62993; Zithromax; Azitrocin; Azythromycin; Azithromycin

Molecular weight: 749.00 g/mol

Molecular formula: C₃₈H₇₂N₂O₁₂

InChI: InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36?,37-,38-/m1/s1

Description

Azithromycin is an antibiotic used for the treatment of a number of bacterial infections (middle ear infections, strep throat, pneumonia, traveller’s diarrhoea) or number of sexually transmitted infections (chlamydia and gonorrhoea infections). Along with other medications, it may also be used for malaria. Recently, the combination of azithromycin with antiviral drug hydroxychloroquine was found to be more efficient in the treatment of COVID-19.

Azithromycin was discovered in 1980 by Pliva and approved for medical use in 1988. It is one of the Essential Medicines in the World Health Organization’s List, the safest and most effective medicines needed in a health system. Azithromycin belongs to family of azalides, a type of macrolide antibiotic. It works by decreasing the production of protein, thereby stopping bacterial growth.

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Payment

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References

Echeverría-Esnal, D., Martin-Ontiyuelo, C., Navarrete-Rouco, M. E., De-Antonio Cuscó, M., Ferrández, O., Horcajada, J. P., & Grau, S. (2021). Azithromycin in the treatment of COVID-19: a review. Expert review of anti-infective therapy, 19(2), 147-163.
Parnham, M. J., Haber, V. E., Giamarellos-Bourboulis, E. J., Perletti, G., Verleden, G. M., & Vos, R. (2014). Azithromycin: mechanisms of action and their relevance for clinical applications. Pharmacology & therapeutics, 143(2), 225-245.
Hopkins, S. (1991). Clinical toleration and safety of azithromycin. The American journal of medicine, 91(3), S40-S45.
Peters, D. H., Friedel, H. A., & McTavish, D. (1992). Azithromycin: a review of its antimicrobial activity, pharmacokinetic properties and clinical efficacy. Drugs, 44(5), 750-799.