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Mizoribine triphosphate – CAS 2744274-19-7

Mizoribine triphosphate – CAS 2744274-19-7 is synthesised by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

97%+

Package contents

Mizoribine triphosphate Et₃NH⁺salt

This compound is for research use only. We do not sell to patients.

Amount

1 mg		€ 3800	Stock
Do you want custom amount?				Custom amount

Amount

1 mg

€ 3800

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 2744274-19-7

IUPAC name: ((2R,3S,4R,5R)-5-(4-carbamoyl-5-hydroxy-1H-imidazol-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate

Other names: bredinin triphosphate; MZB triphosphate

Molecular weight: 499.15 g/mol

Molecular formula: C₉H₁₆N₃O₁₅P₃

InChI: InChI=1S/C9H16N3O15P3/c10-7(15)4-8(16)12(2-11-4)9-6(14)5(13)3(25-9)1-24-29(20,21)27-30(22,23)26-28(17,18)19/h2-3,5-6,9,13-14,16H,1H2,(H2,10,15)(H,20,21)(H,22,23)(H2,17,18,19)/t3-,5-,6-,9-/m1/s1

Description

Mizoribine triphosphate is an active form of drug Mizoribine (brand name Bredinin) that is used as an immunosuppressive drug. Mizoribine (MZB) is an imidazole nucleoside that has been used in renal transplantation, and in steroid-resistant nephrotic syndrome, IgA nephropathy, lupus, as well as for adults with rheumatoid arthritis, lupus nephritis and other rheumatic diseases

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Payment

Payment terms 30 days net
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References

Yokota, S. (2002). Mizoribine: mode of action and effects in clinical use. Pediatrics international, 44(2), 196-198.
Turka, L. A., Dayton, J., Sinclair, G., Thompson, C. B., & Mitchell, B. S. (1991). Guanine ribonucleotide depletion inhibits T cell activation. Mechanism of action of the immunosuppressive drug mizoribine. The Journal of clinical investigation, 87(3), 940-948.