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Mizoribine monophosphate – CAS 62025-48-3

Mizoribine monophosphate – CAS 62025-48-3 is synthesised by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

97%+

Package contents

Mizoribine monophosphate Et₃NH⁺salt

This compound is for research use only. We do not sell to patients.

Amount

1 mg		€ 3700	Stock
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Amount

1 mg

€ 3700

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 62025-48-3, 174498-85-2 (Na+)

IUPAC name: [(2R,3S,4R,5R)-5-(4-carbamoyl-5-hydroxyimidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

Other names: bredinin monophosphate; MZB monophosphate

Molecular weight: 339.20 g/mol

Molecular formula: C₉H₁₄N₃O₉P

InChI: InChI=1S/C9H14N3O9P/c10-7(15)4-8(16)12(2-11-4)9-6(14)5(13)3(21-9)1-20-22(17,18)19/h2-3,5-6,9,13-14,16H,1H2,(H2,10,15)(H2,17,18,19)/t3-,5-,6-,9-/m1/s1

Description

Mizoribine monophosphate is the metabolite of drug Mizoribine (brand name Bredinin) that is used as an immunosuppressive drug. Mizoribine (MZB) is an imidazole nucleoside that has been used in renal transplantation, and in steroid-resistant nephrotic syndrome, IgA nephropathy, lupus, as well as for adults with rheumatoid arthritis, lupus nephritis and other rheumatic diseases

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Payment

Payment terms 30 days net
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References

Yokota, S. (2002). Mizoribine: mode of action and effects in clinical use. Pediatrics international, 44(2), 196-198.
Turka, L. A., Dayton, J., Sinclair, G., Thompson, C. B., & Mitchell, B. S. (1991). Guanine ribonucleotide depletion inhibits T cell activation. Mechanism of action of the immunosuppressive drug mizoribine. The Journal of clinical investigation, 87(3), 940-948.