Maribavir monophosphate – CAS 959366-62-2
Maribavir monophosphate – CAS 959366-62-2 is synthesised by Sigut Labs (Prague, Czech Republic).
Purity (LC-MS)
97%+
Package contents
Maribavir monophosphate Et3NH+ salt
This compound is for research use only. We do not sell to patients.
Amount
| 1 mg | € 4000 | Stock | ||
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Amount
1 mg
€ 4000
Stock
Do you want custom amount?
Custom amount
Characterisation
CAS: 959366-62-2
IUPAC name: ((2R,3S,4R,5R)-5-(5,6-dichloro-2-(isopropylamino)-1H-benzo[d]imidazol-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
Other names: Livtencity monophosphate
Molecular weight: 456.21 g/mol
Molecular formula: C15H20Cl2N3O7P
InChI: InChI=1S/C15H20Cl2N3O7P/c1-6(2)18-15-19-9-3-7(16)8(17)4-10(9)20(15)14-13(22)12(21)11(27-14)5-26-28(23,24)25/h3-4,6,11-14,21-22H,5H2,1-2H3,(H,18,19)(H2,23,24,25)/t11-,12-,13-,14-/m1/s1
Description
Maribavir monophosphate is metabolite of Maribavir, an antiviral drug used to treat post-transplant cytomegalovirus (CMV). Maribavir is a cytomegalovirus pUL97 kinase inhibitor that acts by inhibiting the activity of the human cytomegalovirus enzyme pUL97, halting virus multiplication.
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Payment
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References
- Marty, F. M., Ljungman, P., Papanicolaou, G. A., Winston, D. J., Chemaly, R. F., Strasfeld, L., … & Boeckh, M. (2011). Maribavir prophylaxis for prevention of cytomegalovirus disease in recipients of allogeneic stem-cell transplants: a phase 3, double-blind, placebo-controlled, randomised trial. The Lancet infectious diseases, 11(4), 284-292.
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