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Ganciclovir triphosphate – CAS 86761-38-8

Ganciclovir triphosphate – CAS 86761-38-8 is synthesised by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

97%+

Package contents

Ganciclovir triphosphate Et₃NH⁺salt

This compound is for research use only. We do not sell to patients.

Amount

1 mg	€ 800	Stock
5 mg	€ 2000	Stock
Do you want custom amount?			Custom amount

Amount

1 mg

€ 800

Stock

5 mg

€ 2000

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 86761-38-8

IUPAC name: [[2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]-3-hydroxypropoxy]-hydroxyphosphoryl] phosphono hydrogen phosphate

Other names: DHP-GTP; GCV-TP; GAN-TP

Molecular weight: 495.17 g/mol

Molecular formula: C₉H₁₆N₅O₁₃P₃

InChI: InChI=1S/C9H16N5O13P3/c10-9-12-7-6(8(16)13-9)11-3-14(7)4-24-5(1-15)2-25-29(20,21)27-30(22,23)26-28(17,18)19/h3,5,15H,1-2,4H2,(H,20,21)(H,22,23)(H2,17,18,19)(H3,10,12,13,16)

Description

Ganciclovir triphosphate (also known as ganciclovir-TP) is the active form of the antiviral medication ganciclovir. It works by interfering with the replication of cytomegalovirus (CMV), a type of herpesvirus. Ganciclovir itself needs to be converted inside the body into ganciclovir triphosphate to become effective. This conversion is done by enzymes in CMV-infected cells, making the drug particularly effective against this virus.

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Payment

Payment terms 30 days net
We are sending the invoice the same day as the shipment
We are able to modify the invoice for the academic institution, so the order can be paid from grants

References

Crumpacker, C. S. (1996). Ganciclovir. New England Journal of Medicine, 335(10), 721-729.
Rubsam, L. Z., Boucher, P. D., Murphy, P. J., KuKuruga, M., & Shewach, D. S. (1999). Cytotoxicity and accumulation of ganciclovir triphosphate in bystander cells cocultured with herpes simplex virus type 1 thymidine kinase-expressing human glioblastoma cells. Cancer research, 59(3), 669-675.
St Clair, M. H., Lambe, C. U., & Furman, P. A. (1987). Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information. Antimicrobial agents and chemotherapy, 31(6), 844-849.