(-)-Carbovir triphosphate – CAS 129941-14-6
(-)-Carbovir triphosphate – CAS 129941-14-6 is synthesised by Sigut Labs (Prague, Czech Republic).
Purity (LC-MS)
97%+
Package contents
(-)-Carbovir triphosphate Et3NH+ salt
This compound is for research use only. We do not sell to patients.
Amount
1 mg | € 750 | Stock | ||
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Amount
1 mg
€ 750
Stock
Do you want custom amount?
Custom amount
Characterisation
CAS: 106867-30-5
IUPAC name: [[(1S,4R)-4-(2-amino-6-oxo-1H-purin-9-yl)cyclopent-2-en-1-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Other names: (-)-CBV-TP
Molecular weight: 487.19 g/mol
Molecular formula: C11H16N5O11P3
InChI: InChI=1S/C11H16N5O11P3/c12-11-14-9-8(10(17)15-11)13-5-16(9)7-2-1-6(3-7)4-25-29(21,22)27-30(23,24)26-28(18,19)20/h1-2,5-7H,3-4H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,12,14,15,17)/t6-,7+/m1/s1
Description
(-)-Carbovir triphosphate, also known as (-)-CBV-TP, is a molecule with antiviral properties, specifically targeting the Human Immunodeficiency Virus (HIV). It’s not a directly used medication but an active metabolite of drug Carbovir.
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References
- Hawkins, T., Veikley, W., Claire III, R. L. S., Guyer, B., Clark, N., & Kearney, B. P. (2005). Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens. JAIDS Journal of Acquired Immune Deficiency Syndromes, 39(4), 406-411.
- White, E. L., Parker, W. B., Macy, L. J., Shaddix, S. C., McCaleb, G., Secrist III, J. A., … & Shannon, W. M. (1989). Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases. Biochemical and biophysical research communications, 161(2), 393-398.
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