BDP FL maleimide – CAS 773859-49-7

BDP FL maleimide – CAS 773859-49-7 is provided by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

95%+

Package contents

BDP FL maleimide

This compound is for research use only. We do not sell to patients. 

Amount
25 mg
€ 500

Stock

100 mg
€ 1400

Stock

250 mg
€ 2900

Stock

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Amount
25 mg
€ 500

Stock

100 mg
€ 1400

Stock

250 mg
€ 2900

Stock

View more amounts
Do you want custom amount?
Custom amount

Characterisation

CAS: 773859-49-7
IUPAC name: 3-(2,2-difluoro-10,12-dimethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl)-N-[2-(2,5-dioxopyrrol-1-yl)ethyl]propanamide
Other names: BDP FL maleimide, F01-0013, BP-22550
Molecular weight: 414.2 g/mol
Molecular formula: C20H21BF2N4O3
InChI: InChI=1S/C20H21BF2N4O3/c1-13-11-14(2)26-17(13)12-16-4-3-15(27(16)21(26,22)23)5-6-18(28)24-9-10-25-19(29)7-8-20(25)30/h3-4,7-8,11-12H,5-6,9-10H2,1-2H3,(H,24,28)
Solubility: Good in organic solvents (DMF, DMSO, dichloromethane), limited in water
Excitation/absorption maximum: 503 nm
Emission maximum: 509 nm
Extinction Coefficient: 92000 M-1cm-1

Description

Introducing Thiol-reactive BDP FL maleimide, a dynamic dye engineered for efficient protein labeling.

Derived from the borondipyrromethene family, BDP FL maleimide shares absorption and fluorescence spectra characteristics with fluorescein (FAM). What sets this dye apart is its exceptional photostability, making it an ideal choice for a variety of applications. With a non-charged nature and low molecular weight, BDP FL maleimide matches the brightness of fluorescein, R110, and xanthene dye derivatives.

This versatile fluorophore finds its excellence in fluorescent microscopy and various other applications. Offering a seamless substitution for fluorescein across a wide range of applications, BDP FL maleimide is compatible with any FAM-capable fluorescent instrumentation, making it a valuable addition to your research toolkit. Elevate your experiments with the superior qualities of thiol-reactive BDP FL maleimide.

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References

  • Buecheler JW, Winzer M, Tonillo J, Weber C, Gieseler H. Impact of Payload Hydrophobicity on the Stability of Antibody-Drug Conjugates. Mol Pharm. 2018;15(7):2656-2664. doi:10.1021/acs.molpharmaceut.8b00177

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