Abacavir diphosphate – CAS 136522-28-6
Abacavir diphosphate – CAS 136522-28-6 is synthesised by Sigut Labs (Prague, Czech Republic).
Purity (LC-MS)
97%+
Package contents
Abacavir diphosphate Et3NH+ salt
This compound is for research use only. We do not sell to patients.
Amount
| 1 mg | € 800 | Stock | ||
| 5 mg | € 2500 | Stock | ||
| Do you want custom amount? | Custom amount | |||
Amount
1 mg
€ 800
Stock
5 mg
€ 2500
Stock
Do you want custom amount?
Custom amount
Characterisation
CAS: 136522-28-6
IUPAC name: ((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methyl trihydrogen diphosphate
Other names: Abacavir DP; ABAC-DP
Molecular weight: 446.30 g/mol
Molecular formula: C14H20N6O17P2
InChI: InChI=1S/C14H20N6O7P2/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-26-29(24,25)27-28(21,22)23/h1,4,7-10H,2-3,5-6H2,(H,24,25)(H2,21,22,23)(H3,15,17,18,19)/t8-,10+/m1/s1
Description
Abacavir diphosphate (ABAC-DP) is a metabolite of the antiviral drug Abacavir, widely used in HIV treatment regimens.
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Payment
- Payment terms 30 days net
- We are sending the invoice the same day as the shipment
- We are able to modify the invoice for the academic institution, so the order can be paid from grants
References
- Singh, D., McMillan, J., Hilaire, J., Gautam, N., Palandri, D., Alnouti, Y., … & Edagwa, B. (2016). Development and characterization of a long-acting nanoformulated abacavir prodrug. Nanomedicine, 11(15), 1913-1927.
- Boojamra, C. G., Parrish, J. P., Sperandio, D., Gao, Y., Petrakovsky, O. V., Lee, S. K., … & Mackman, R. L. (2009). Design, synthesis, and anti-HIV activity of 4′-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitors. Bioorganic & Medicinal Chemistry, 17(4), 1739-1746.
- Gendelman, H. E., McMillan, J., Bade, A. N., Edagwa, B., & Kevadiya, B. D. (2019). The promise of long-acting antiretroviral therapies: from need to manufacture. Trends in microbiology, 27(7), 593-606.
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