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7-iodo-7-deaza-2′-deoxyguanosine triphosphate – CAS 244109-12-4

7-iodo-7-deaza-2′-deoxyguanosine triphosphate – CAS 244109-12-4 is synthesised by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

95%+

Package contents

7-iodo-7-deaza-2′-deoxyguanosine triphosphate Et₃NH⁺salt

This compound is for research use only. We do not sell to patients.

Amount

1 mg	€ 500	Stock
5 mg	€ 1600	Stock
Do you want custom amount?			Custom amount

Amount

1 mg

€ 500

Stock

5 mg

€ 1600

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 244109-12-4

IUPAC name: ((2R,3S,5R)-5-(2-amino-5-iodo-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate

Other names:

Molecular weight: 632.09 g/mol

Molecular formula: C₁₁H₁₆N₄O₁₃P₃I

InChI: InChI=1S/C11H16IN4O13P3/c12-4-2-16(9-8(4)10(18)15-11(13)14-9)7-1-5(17)6(27-7)3-26-31(22,23)29-32(24,25)28-30(19,20)21/h2,5-7,17H,1,3H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,13,14,15,18)/t5-,6+,7+/m0/s1

Description

7-iodo-7-deaza-2′-deoxyguanosine triphosphate is a metabolite of 7-Deaza-2′-deoxy-7-iodoguanosine, a purine nucleoside that is synthesized from guanosine and iodine. It is used as a marker in sequencing reactions because it can be easily detected by UV light at 254 nm.

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Payment

Payment terms 30 days net
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References

Seela, F., Feiling, E., Gross, J., Hillenkamp, F., Ramzaeva, N., Rosemeyer, H., & Zulauf, M. (2001). Fluorescent DNA: the development of 7-deazapurine nucleoside triphosphates applicable for sequencing at the single molecule level. Journal of Biotechnology, 86(3), 269-279.
Seela, F., Ramzaeva, N., & Chen, Y. (1995). Oligonucleotide duplex stability controlled by the 7-substituents of 7-deazaguanine bases. Bioorganic & Medicinal Chemistry Letters, 5(24), 3049-3052.