7-iodo-7-deaza-2′-deoxyguanosine triphosphate – CAS 244109-12-4
7-iodo-7-deaza-2′-deoxyguanosine triphosphate – CAS 244109-12-4 is synthesised by Sigut Labs (Prague, Czech Republic).
Purity (LC-MS)
95%+
Package contents
7-iodo-7-deaza-2′-deoxyguanosine triphosphate Et3NH+ salt
This compound is for research use only. We do not sell to patients.
Amount
1 mg | € 500 | Stock | ||
5 mg | € 1600 | Stock | ||
Do you want custom amount? | Custom amount |
Amount
1 mg
€ 500
Stock
5 mg
€ 1600
Stock
Do you want custom amount?
Custom amount
Characterisation
CAS: 244109-12-4
IUPAC name: ((2R,3S,5R)-5-(2-amino-5-iodo-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
Other names:
Molecular weight: 632.09 g/mol
Molecular formula: C11H16N4O13P3I
InChI: InChI=1S/C11H16IN4O13P3/c12-4-2-16(9-8(4)10(18)15-11(13)14-9)7-1-5(17)6(27-7)3-26-31(22,23)29-32(24,25)28-30(19,20)21/h2,5-7,17H,1,3H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,13,14,15,18)/t5-,6+,7+/m0/s1
Description
7-iodo-7-deaza-2′-deoxyguanosine triphosphate is a metabolite of 7-Deaza-2′-deoxy-7-iodoguanosine, a purine nucleoside that is synthesized from guanosine and iodine. It is used as a marker in sequencing reactions because it can be easily detected by UV light at 254 nm.
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Payment
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References
- Seela, F., Feiling, E., Gross, J., Hillenkamp, F., Ramzaeva, N., Rosemeyer, H., & Zulauf, M. (2001). Fluorescent DNA: the development of 7-deazapurine nucleoside triphosphates applicable for sequencing at the single molecule level. Journal of Biotechnology, 86(3), 269-279.
- Seela, F., Ramzaeva, N., & Chen, Y. (1995). Oligonucleotide duplex stability controlled by the 7-substituents of 7-deazaguanine bases. Bioorganic & Medicinal Chemistry Letters, 5(24), 3049-3052.
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