7-iodo-7-deaza-2′-deoxyguanosine monophosphate – CAS 1190922-17-8

7-iodo-7-deaza-2′-deoxyguanosine monophosphate – CAS 1190922-17-8 is synthesised by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

95%+

Package contents

7-iodo-7-deaza-2′-deoxyguanosine monophosphate Et3NH+ salt

This compound is for research use only. We do not sell to patients.

 

Amount
1 mg
€ 500

Stock

5 mg
€ 1600

Stock

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Amount
1 mg
€ 500

Stock

5 mg
€ 1600

Stock

Do you want custom amount?
Custom amount

Characterisation

CAS: 1190922-17-8
IUPAC name: ((2R,3S,5R)-5-(2-amino-5-iodo-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
Other names:    
Molecular weight: 472.13 g/mol
Molecular formula:  C11H14N4O7PI
InChI: InChI=1S/C11H14IN4O7P/c12-4-2-16(9-8(4)10(18)15-11(13)14-9)7-1-5(17)6(23-7)3-22-24(19,20)21/h2,5-7,17H,1,3H2,(H2,19,20,21)(H3,13,14,15,18)/t5-,6+,7+/m0/s1

Description

7-iodo-7-deaza-2′-deoxyguanosine monophosphate is a metabolite of 7-deaza-2′-deoxy-7-iodoguanosine, a purine nucleoside that is synthesized from guanosine and iodine. It is used as a marker in sequencing reactions because it can be easily detected by UV light at 254 nm.

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Payment

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References

  • Seela, F., Feiling, E., Gross, J., Hillenkamp, F., Ramzaeva, N., Rosemeyer, H., & Zulauf, M. (2001). Fluorescent DNA: the development of 7-deazapurine nucleoside triphosphates applicable for sequencing at the single molecule level. Journal of Biotechnology86(3), 269-279.
  • Seela, F., Ramzaeva, N., & Chen, Y. (1995). Oligonucleotide duplex stability controlled by the 7-substituents of 7-deazaguanine bases. Bioorganic & Medicinal Chemistry Letters5(24), 3049-3052.
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