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5-iododeoxycytidine triphosphate – CAS 31747-59-8

5-iododeoxycytidine triphosphate – CAS 31747-59-8 is synthesised by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

95%+

Package contents

5-iododeoxycytidine triphosphate Et₃NH⁺salt

This compound is for research use only. We do not sell to patients.

Amount

1 mg	€ 400	Stock
5 mg	€ 1200	Stock
Do you want custom amount?			Custom amount

Amount

1 mg

€ 400

Stock

5 mg

€ 1200

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 31747-59-8; 1646812-23-8 (Et3NH+)

IUPAC name: [[(2R,3S,5R)-5-(4-amino-5-iodo-2-oxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

Other names: IdCTP; 5-iodo-dCTP

Molecular weight: 593.05 g/mol

Molecular formula: C₉H₁₅IN₃O₁₃P₃

InChI: InChI=1S/C9H15IN3O13P3/c10-4-2-13(9(15)12-8(4)11)7-1-5(14)6(24-7)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h2,5-7,14H,1,3H2,(H,19,20)(H,21,22)(H2,11,12,15)(H2,16,17,18)/t5-,6+,7+/m0/s1

Description

5-iododeoxycytidine triphosphate is a 2′-deoxycytidine phosphate, or 2′-deoxycytidine-5′-triphosphate, in which iodine replaces the hydrogen at position 5 on the cytosine ring. It’s a 2′-deoxycytidine phosphate and an organoiodine molecule. It is functionally similar to a dCTP.

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Payment

Payment terms 30 days net
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References

Creasey, W. A. (1963). Studies on the Metabolism of 5-Iodo-2′-deoxycytidine in Vitro: PURIFICATION OF NUCLEOSIDE DEAMINASE FROM MOUSE KIDNEY. Journal of Biological Chemistry, 238(5), 1772-1776.
Münzel, M., Lischke, U., Stathis, D., Pfaffeneder, T., Gnerlich, F. A., Deiml, C. A., … & Carell, T. (2011). Improved synthesis and mutagenicity of oligonucleotides containing 5‐hydroxymethylcytosine, 5‐formylcytosine and 5‐carboxylcytosine. Chemistry–A European Journal, 17(49), 13782-13788.
Cahová, H., & Jäschke, A. (2013). Nucleoside‐Based Diarylethene Photoswitches and Their Facile Incorporation into Photoswitchable DNA. Angewandte Chemie International Edition, 52(11), 3186-3190.