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5′-Azacytidine triphosphate – CAS 2226-74-6

5′-Azacytidine triphosphate – CAS 2226-74-6 is synthesised by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

95%+

Package contents

5′-Azacytidine triphosphate Et₃NH⁺salt

This compound is for research use only. We do not sell to patients.

Amount

1 mg		€ 3500	Stock
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Amount

1 mg

€ 3500

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 2226-74-6

IUPAC name: [[(2S,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]amino] [hydroxy(phosphonooxy)phosphoryl] hydrogen phosphate

Other names: 5′-Azacytidine 5′-triphosphate; DB-225240; 5-aza-CTP

Molecular weight: 484.14 g/mol

Molecular formula: C₈H₁₅N₄O₁₄P₃

InChI: InChI=1S/C8H15N4O14P3/c9-3-1-2-12(8(15)10-3)7-5(14)4(13)6(23-7)11-24-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4-7,11,13-14H,(H,19,20)(H,21,22)(H2,9,10,15)(H2,16,17,18)/t4-,5+,6-,7+/m0/s1

Description

5′-Azacytidine triphosphate (5-aza-CTP) is a cytidine analog that inhibits the incorporation of [3H]CTP, but not [3H]UTP, into RNA during the DNA-dependent RNA polymerase process.

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Payment

Payment terms 30 days net
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References

Čihák, A. (1974). Biological effects of 5-azacytidine in eukaryotes: A Review. Oncology, 30(5), 405-422.
Lee, T. T., & Momparler, R. L. (1976). Enzymatic synthesis of 5-azacytidine 5′-triphosphate from 5-azacytidine. Analytical Biochemistry, 71(1), 60-67.
McPartland, R. P., Wang, M. C., Bloch, A., & Weinfeld, H. (1974). Cytidine 5′-triphosphate synthetase as a target for inhibition by the antitumor agent 3-deazauridine. Cancer Research, 34(11), 3107-3111.