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4-(1-(tert-butyl)-3-cyclobutyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzonitrile

4-(1-(tert-butyl)-3-cyclobutyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzonitrile is synthesised by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

95%+

Package contents

4-(1-(tert-butyl)-3-cyclobutyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzonitrile

This compound is for research use only. We do not sell to patients.

Amount

10 mg	€ 800	Stock
50 mg	€ 2000	Stock
Do you want custom amount?			Custom amount

Amount

10 mg

€ 800

Stock

50 mg

€ 2000

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: N.A.

IUPAC name: 4-(1-(tert-butyl)-3-cyclobutyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzonitrile

Other names:

Molecular weight: 346.43 g/mol

Molecular formula: C₂₁H₂₂N₄O

InChI: InChI=1S/C21H22N4O/c1-21(2,3)25-19-17(18(24-25)15-5-4-6-15)11-16(20(26)23-19)14-9-7-13(12-22)8-10-14/h7-11,15H,4-6H2,1-3H3,(H,23,26)

Description

4-(1-(tert-butyl)-3-cyclobutyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzonitrile is a unique building block. Related compounds were studied for their properties to inhibit cyclin-dependent kinases (CDK) and glycogen synthase kinase 3 (GSK-3).

Chemicals are distributed worldwide

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Payment

Payment terms 30 days net
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References

Vidula, N., & Rugo, H. S. (2016). Cyclin-dependent kinase 4/6 inhibitors for the treatment of breast cancer: a review of preclinical and clinical data. Clinical breast cancer, 16(1), 8-17.
Wager, T., T. Pyrazolo`3,4-bipiridin-6-ones as GSK-3 inhibitors. 2005, patent number WO2005000303.