3′,4′-Didehydro-3′-deoxyuridine triphosphate – CAS 2499590-38-2

3′,4′-Didehydro-3′-deoxyuridine triphosphate – CAS 2499590-38-2 is synthesized by Sigut Labs (Prague, Czech Republic). 

Purity (LC-MS)

min 95%

Package contents

3′,4′-Didehydro-3′-deoxyuridine triphosphate triethylammonium salt

This compound is for research use only. We do not sell to patients.

Amount
1 mg
€ 3100

Stock

5 mg
€ 5900

Stock

Do you want custom amount?
Custom amount
Amount
1 mg
€ 3100

Stock

5 mg
€ 5900

Stock

Do you want custom amount?
Custom amount

Characterisation

CAS: 2499590-38-2, 2787607-83-2 (Et3NH+ salt)
IUPAC name: ((4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-4,5-dihydrofuran-2-yl)methyl tetrahydrogen triphosphate
Other names: DdhU-TP, Ddh-U triphosphate, 3′,4′-Didehydro-3′-deoxyuridine triphosphate
Molecular weight: 466.12 g/mol
Molecular formula: C9H13N2O14P3
InChI: InChI=1S/C9H13N2O14P3/c12-6-3-5(23-8(6)11-2-1-7(13)10-9(11)14)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-3,6,8,12H,4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17)/t6-,8-/m1/s1

Description

3′,4′-Didehydro-3′-deoxyuridine triphosphate is a metabolite of 3′,4′-Didehydro-3′-deoxyuridine (DdhU). A related compound,  3′,4′-didehydro-3′-deoxycytidine triphosphate has been proven to have antiviral properties. It has the ability to prevent the replication of several viruses, including the Zika virus. This molecule is naturally produced in mammals through the dehydration of cytidine triphosphate (CTP), which is catalyzed by the enzyme viperin.

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Payment

  • We are sending the invoice the same day as the shipment
  • We are able to modify the invoice for the academic institution, so the order can be paid from grants

References

  • WO2021133854 A1 2021-07-01
  • WO2020202142 A2 2020-10-08
  • WO2022123501 A1 2022-06-16
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