Home → E-shop → Nucleotides → 3′,4′-Didehydro-3′-deoxyuridine monophosphate – CAS 2499590-42-8

3′,4′-Didehydro-3′-deoxyuridine monophosphate – CAS 2499590-42-8

3′,4′-Didehydro-3′-deoxyuridine monophosphate – CAS 2499590-42-8 is synthesized by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

min 95%

Package contents

3′,4′-Didehydro-3′-deoxyuridine monophosphate triethylammonium salt

This compound is for research use only. We do not sell to patients.

Amount

1 mg	€ 2500	Stock
5 mg	€ 4400	Stock
Do you want custom amount?			Custom amount

Amount

1 mg

€ 2500

Stock

5 mg

€ 4400

Stock

Do you want custom amount?

Custom amount

Characterisation

CAS: 2499590-42-8

IUPAC name: ((4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-4,5-dihydrofuran-2-yl)methyl dihydrogen phosphate

Other names: DdhU-MP, Ddh-U monophosphate, 3′,4′-Didehydro-3′-deoxyuridine monophosphate

Molecular weight: 306.17 g/mol

Molecular formula: C₉H₁₁N₂O₈P

InChI: InChI=1S/C9H11N2O8P/c12-6-3-5(4-18-20(15,16)17)19-8(6)11-2-1-7(13)10-9(11)14/h1-3,6,8,12H,4H2,(H,10,13,14)(H2,15,16,17)/t6-,8-/m1/s1

Description

3′,4′-Didehydro-3′-deoxyuridine monophosphate is a metabolite of 3′,4′-Didehydro-3′-deoxyuridine (DdhU). A related compound, 3′,4′-didehydro-3′-deoxycytidine triphosphate has been proven to have antiviral properties. It has the ability to prevent the replication of several viruses, including the Zika virus. This molecule is naturally produced in mammals through the dehydration of cytidine triphosphate (CTP), which is catalyzed by the enzyme viperin.

Chemicals are distributed worldwide

Buy 3′,4′-Didehydro-3′-deoxyuridine monophosphate now, and get your order in 48 hours

Shipping through DHL in 48 hours
All compounds are safely and rigorously packed

Payment

We are sending the invoice the same day as the shipment
We are able to modify the invoice for the academic institution, so the order can be paid from grants

References

Petrová, M., Buděšínský, M., & Rosenberg, I. (2010). Straightforward synthesis of 3′-deoxy-3′, 4′-didehydronucleoside-5′-aldehydes via 2′, 3′-O-orthoester group elimination: a simple route to 3′, 4′-didehydronucleosides. Tetrahedron Letters, 51(52), 6874-6876.
WO2020202142 A2 2020-10-08
US3457255 A 1969-07-22
WO2022038539 A2 2022-02-24