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Remdesivir O-desphosphate acetonide – CAS 1191237-80-5

Remdesivir O-desphosphate acetonide (CAS 1191237-80-5) is synthesized by Sigut Labs (Prague, Czech Republic).

Purity (LC-MS)

99 %

Package contents

Remdesivir O-desphosphate acetonide

This compound is for research use only. We do not sell to patients.

Amount

100 mg	€ 400	Stock
500 mg	€ 600	Stock
1 g	€ 800	Stock
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Amount

100 mg

€ 400

Stock

500 mg

€ 600

Stock

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Characterisation

CAS: 1191237-80-5

IUPAC name: D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-3,4-O-(1-methylethylidene)-

Other names: Remdesivir O-desphosphate acetonide impurity, AC-31304

Molecular weight: 331.33 g/mol

Molecular formula: C₁₅H₁₇N₅O₄

InChI: InChI=1S/C15H17N5O4/c1-14(2)23-11-9(5-21)22-15(6-16,12(11)24-14)10-4-3-8-13(17)18-7-19-20(8)10/h3-4,7,9,11-12,21H,5H2,1-2H3,(H2,17,18,19)/t9-,11-,12-,15+/m1/s1

Description

Remdesivir O-desphosphate acetonide is an essential building block to the synthesis of Remdesivir triphosphate (1355149-45-9) and Remdesivir (1809249-37-3). Nucleoside derivate is used in the treatment of Feline infectious peritonitis (FIP). This fatal disease affects cats and is caused by a virus from a group of coronavirus. Remdesivir is nucleoside prodrug that metabolizes into GS-441524 which is phosphorylated to Remdesivir triphosphate. This phosphorus analog is mainly an active compound in the treatment of Ebola and COVID-19.

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Payment

Payment terms 30 days net
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References

Al Bujuq, N. (2020). Methods of synthesis of remdesivir, favipiravir, hydroxychloroquine, and chloroquine: four small molecules repurposed for clinical trials during the covid-19 pandemic. Synthesis, 52(24), 3735-3750.