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1-(tert-butyl)-3-cyclobutyl-5-(p-tolyl)-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one
1-(tert-butyl)-3-cyclobutyl-5-(p-tolyl)-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one is synthesised by Sigut Labs (Prague, Czech Republic).
Purity (LC-MS)
95%+
Package contents
1-(tert-butyl)-3-cyclobutyl-5-(p-tolyl)-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one
This compound is for research use only. We do not sell to patients.
Amount
| 10 mg | € 800 | Stock | ||
| 50 mg | € 2000 | Stock | ||
| Do you want custom amount? | Custom amount | |||
Amount
10 mg
€ 800
Stock
50 mg
€ 2000
Stock
Do you want custom amount?
Custom amount
Characterisation
CAS: N.A.
IUPAC name: 1-(tert-butyl)-3-cyclobutyl-5-(p-tolyl)-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one
Other names:
Molecular weight: 335.45 g/mol
Molecular formula: C21H25N3O
InChI: InChI=1S/C21H25N3O/c1-13-8-10-14(11-9-13)16-12-17-18(15-6-5-7-15)23-24(21(2,3)4)19(17)22-20(16)25/h8-12,15H,5-7H2,1-4H3,(H,22,25)
Description
1-(tert-butyl)-3-cyclobutyl-5-(p-tolyl)-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one is a unique building block. Related compounds were studied for their properties to inhibit cyclin-dependent kinases (CDK) and glycogen synthase kinase 3 (GSK-3).
Chemicals are distributed worldwide
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Payment
- Payment terms 30 days net
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References
- Vidula, N., & Rugo, H. S. (2016). Cyclin-dependent kinase 4/6 inhibitors for the treatment of breast cancer: a review of preclinical and clinical data. Clinical breast cancer, 16(1), 8-17.
- Wager, T., T. Pyrazolo`3,4-bipiridin-6-ones as GSK-3 inhibitors. 2005, patent number WO2005000303.
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